A Randomized Trial of Modified-Release Versus Immediate-Release Tolvaptan in ADPKD
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چکیده
منابع مشابه
Pharmacokinetics and Pharmacodynamics of Gliclazide from Immediate and Modified Release Formulation Tablets in Rats
The objective of the study was to compare pharmacokinetic and pharmacodynamic parameters of gliclazide after administration of immediate (IR) and modified release (MR) tablets. The experiment included rats with both normoglyceamia and streptozocin (STZ)-induced hyperglyceamia. Several MR formulations were designed and in vitro drug release profile was assessed by a dissolution test. For the fur...
متن کاملPharmacokinetics and Pharmacodynamics of Gliclazide from Immediate and Modified Release Formulation Tablets in Rats
The objective of the study was to compare pharmacokinetic and pharmacodynamic parameters of gliclazide after administration of immediate (IR) and modified release (MR) tablets. The experiment included rats with both normoglyceamia and streptozocin (STZ)-induced hyperglyceamia. Several MR formulations were designed and in vitro drug release profile was assessed by a dissolution test. For the fur...
متن کاملTapentadol immediate release versus oxycodone immediate release for treatment of acute low back pain.
BACKGROUND Tapentadol has demonstrated analgesic efficacy across a range of pain conditions. OBJECTIVE In a head-to-head study of up to 10 days in duration, the analgesic efficacy and tolerability of tapentadol immediate release (IR) versus oxycodone IR using a flexible dosing regimen were compared in patients with acute low back pain (LBP) and associated radicular leg pain. STUDY DESIGN Ra...
متن کاملImmediate Effect of Active Release Technique versus Mulligan Bent Leg Raise in Subjects with Hamstring Tightness: a Randomized Clinical Trial
Background: To study and compare the effectiveness of active release technique and mulligan bent leg raise in subjects with hamstring tightness. Methods: 40 normal healthy subjects (20 in each group) were recruited in the study under simple randomization method. Group A received single session of Active Release Technique and Group B received single session of Mulligan Bent Leg Raise technique f...
متن کاملComparison of modified posteromedial release and complete subtalar release in resistant congenital clubfoot: a randomized controlled trial.
OBJECTIVE To compare the surgical results of modified posteromedial release with modified complete subtalar release in resistant congenital clubfoot in a randomized controlled trial MATERIAL AND METHOD Eighty six children with 128 clubfeet, at an average of 5.9 months old (3-12 months) were operated on between 1996 and 2006 by a single surgeon. They were randomized into two groups. Group A, t...
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ژورنال
عنوان ژورنال: Kidney International Reports
سال: 2020
ISSN: 2468-0249
DOI: 10.1016/j.ekir.2020.03.013